Abstract

abstract: “Effective control of porcine reproductive and respiratory syndrome virus (PRRSV) remains a challenge for the swine industry. This study developed a mathematical model to evaluate PRRSV transmission dynamics and the effectiveness of different vaccination strategies within commercial swine populations. The model incorporates between-farm movement data and local transmission risks to simulate virus spread. Various vaccination scenarios were tested, including mass vaccination and targeted vaccination of high-risk farms. The results demonstrate that while mass vaccination significantly reduces overall prevalence, targeted vaccination based on network centrality can be a more efficient resource allocation strategy. The findings provide quantitative support for the development of more effective regional PRRSV control programs.”