The Machado Lab is led by Gustavo Machado, an associate professor at the North Carolina State University, College of Veterinary Medicine at the Department of Population Health and Pathobiology, with an affiliation with the Center for Geospatial Analytics.
I am an Associate Professor of Transboundary disease epidemiology in the Population Health and Pathobiology department, and is also affiliated with the Biomathematics graduate program and with the Center for Geospatial Analytics at NCSU. I am an infectious disease modeler with expertise in food animal production epidemiology and the development of novel disease control strategies at multiple scales to reduce the burden of endemic and emerging diseases. I have worked on several aspects of disease modeling approaches, including the development of mathematical models fitted to actual population, animal, and vehicle movement data, and modeling the epidemiology and disease spread dynamics of several animal diseases, including African swine fever, foot-and-mouth disease, porcine reproductive and respiratory syndrome virus, and porcine epidemic diarrhea virus. I have experience in the regulatory aspects of disease control work nationally and internationally, including Brazil. At NC State University, I teach courses on the epidemiology of infectious diseases. My research laboratory specializes in mathematical models of livestock diseases and develops novel strategies for their control and elimination. We engage with and provide training for government and industry stakeholders and academics nationally and internationally.
Selected publications
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A discrete-time survival model for porcine epidemic diarrhoea virus Parker Trostle, Cesar A. Corzo, Brian J. Reich, Gustavo Machado Transboundary and Emerging Diseases |
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Modeling between-farm transmission dynamics of porcine epidemic diarrhea virus: Characterizing the dominant transmission routes Jason A.Galvis, Cesar A.Corzo, Joaquín M.Prada, Gustavo Machado Preventive Veterinary Medicine |
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Coupling spatial statistics with social network analysis to estimate distinct risk areas of disease circulation to improve risk-based surveillance Nicolas C. Cardenas, Felipe Sanchez, Francisco P. N. Lopes, Gustavo Machado Transboundary and Emerging Diseases |
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Multiple species animal movements: network properties, disease dynamics and the impact of targeted control actions Nicolas C. Cardenas, Abagael L. Sykes, Francisco P. N. Lopes, Gustavo Machado Veterinary Research |
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The ecology of chronic wasting disease in wildlife Escobar LE,Pritzkow S,Winter SN,Grear DA,Kirchgessner MS,Dominguez-Villegas E,Machado, Gustavo,Townsend Peterson A,Soto C Biological Reviews 393-408 |
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Nairobi sheep disease virus: a historical and epidemiological perspective Krasteva S,Jara M,Frias-De AF,Machado, Gustavo Front Vet Sci |
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Information differences across spatial resolutions and scales for disease surveillance and analysis: The case of Visceral Leishmaniasis in Brazil Servadio JL,Machado, Gustavo,Alvarez J,de Ferreira Lima Junior FE,Vieira Alves R,Convertino M PloS one e0235920 |
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Quantifying the dynamics of pig movements improves targeted disease surveillance and control plans Machado, Gustavo,Galvis JA,Lopes FP,Voges J,Medeiros AA,C?<U+FFFD>rdenas NC Transboundary and Emerging Diseases |
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Burkholderia mallei: The dynamics of networks and disease transmission Cardenas NC,Galvis JO,Farinati AA,Grisi-Filho JH,Diehl GN,Machado, Gustavo Transboundary and emerging diseases 715-728 |
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Prevalence of and factors associated with feline leukemia virus FeLV and feline immunodeficiency virus FIV in cats of the state of Santa Catarina, Brazil Biezus G,Machado, Gustavo,Ferian PE,da Costa UM,da Silva Pereira LH,Withoeft JA,Nunes IA,Muller TR,de Cristo TG,Casagrande RA Comparative immunology, microbiology and infectious diseases 17-21 |
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Revisiting area risk classification of visceral leishmaniasis in Brazil Machado, Gustavo,Alvarez J,Bakka HC,Perez A,Donato LE,Junior FE,Alves RV,Vilas VJ BMC infectious diseases 9-Jan |
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Identifying outbreaks of Porcine Epidemic Diarrhea virus through animal movements and spatial neighborhoods Machado, Gustavo,Vilalta C,Recamonde-Mendoza M,Corzo C,Torremorell M,Perez A,VanderWaal K Scientific reports 12-Jan |
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Mapping changes in the spatiotemporal distribution of lumpy skin disease virus Machado, Gustavo,Korennoy F,Alvarez J,Picasso-Risso C,Perez A,VanderWaal K Transboundary and emerging diseases 2045-2057 |
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A one health approach to investigating leptospira serogroups and their spatial distributions among human and animals in Rio Grande do Sul, Brazil, 2013-2015 Polo N,Machado, Gustavo,Rodrigues R,Njera Hamrick P,Munoz-Zanzi C,Pereira MM,Bercini M,Timm LN,Schneider MC Tropical medicine and infectious disease 42 |
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Spatial distribution and spread potential of sixteen Leptospira serovars in a subtropical region of Brazil Jara M,Escobar LE,Rodriges RO,Frias-De-Diego A,Sanhueza J,Machado, Gustavo Transboundary and emerging diseases 2482-2495 |
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Molecular serotyping of clinical strains of Haemophilus Glaesserella parasuis brings new insights regarding Glasser disease outbreaks in Brazil Espandola JP,Balbinott N,Gressler LT,Machado, Gustavo,Klein CS,Rebelatto R,Martin CB,Kreutz LC,Schryvers AB,Frandoloso R PeerJ e6817 |
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Individual or common good? Voluntary data sharing to inform disease surveillance systems in food animals Perez AM,Linhares DC,Arruda AG,VanderWaal K,Machado, Gustavo,Vilalta C,Sanhueza JM,Torrison J,Torremorell M,Corzo CA Frontiers in veterinary science 194 |
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Single fragment or bulk soil DNA metabarcoding: which is better for characterizing biological taxa found in surface soils for sample separation? Boggs LM,Scheible MK,Machado, Gustavo,Meiklejohn KA Genes 431 |
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Machine-learning algorithms to identify key biosecurity practices and factors associated with breeding herds reporting PRRS outbreak Silva GS,Machado, Gustavo,Baker KL,Holtkamp DJ,Linhares DC Preventive veterinary medicine 104749 |
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How to make more from exposure data? An integrated machine learning pipeline to predict pathogen exposure Fountain-Jones NM,Machado, Gustavo,Carver S,Packer C,Recamonde-Mendoza M,Craft ME Journal of Animal Ecology 1447-1461 |
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Use of a voluntary testing program to study the spatial epidemiology of Johne's disease affecting dairy herds in Minnesota: a cross sectional study Kanankege KST,Machado, Gustavo,Zhang L,Dokkebakken B,Schumann V,Wells SJ,Perez AM,Alvarez J BMC veterinary research 11-Jan |
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Prevalence of Rhodococcus equi from the nasal cavity of 1010 apparently healthy horses Gressler LT,Machado, Gustavo,da Silveira BP,Cohen ND,Corbellini LG,Leotti VB,Diehl GN,Dos Santos LC,de Vargas AC Equine veterinary journal 667-671 |
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Identifying individual animal factors associated with Mycobacterium avium subsp. paratuberculosis MAP milk ELISA positivity in dairy cattle in the Midwest region of the United States Machado, Gustavo,Kanankege K,Schumann V,Wells S,Perez A,Alvarez J BMC veterinary research 8-Jan |
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Potential distribution of Pythium insidiosum in Rio Grande do Sul, Brazil, and projections to neighbour countries Machado, Gustavo,Weiblen C,Escobar LE Transboundary and emerging diseases 1671-1679 |
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Spatiotemporal dynamics and risk factors for human Leptospirosis in Brazil Baquero OS,Machado, Gustavo Scientific reports 14-Jan |